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Search Results for " Serine proteases "

ターゲット

Endogenous Metabolite Bradykinin Receptor

阻害剤

天然化合物

リコンビナントタンパク質

TargetMolキット

カタログ番号	製品名	別名	ターゲット
TP1277	Bradykinin		Endogenous Metabolite , Bradykinin Receptor
	Bradykinin is an inflammatory mediator. It is a peptide that causes blood vessels to dilate (enlarge) via the release of prostacyclin, nitric oxide, and Endothelium-Derived Hyperpolarizing Factor. Bradykinin is a physiol...		Endogenous Metabolite , Bradykinin Receptor
T11666	IPR-803		Serine/threonin kinase
	IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity. IPR-803 binds directly to uPAR with a Ki of 0.2 μM.		Serine/threonin kinase
T11885	LSP-249		Others
	LSP-249 is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell.		Others
T7017	WNK463		Serine/threonin kinase
	WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).		Serine/threonin kinase
T4058	R-IMPP		Others , Serine/threonin kinase
	R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.		Others , Serine/threonin kinase
T10547	BioE-1115		Serine/threonin kinase , Casein Kinase
			Serine/threonin kinase , Casein Kinase
T8350	TPCK		Proteasome
	TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis		Proteasome
T13257	Upamostat		PAI-1 , Serine/threonin kinase , Serine Protease
	Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.		PAI-1 , Serine/threonin kinase , Serine Protease
T8362	Benzamidine hydrochloride	Benzamidine HCl	Serine/threonin kinase , Serine Protease
	Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively).		Serine/threonin kinase , Serine Protease
T4524	SBC-110736	SBC110736	Others , Serine/threonin kinase
	SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor		Others , Serine/threonin kinase
T9920	Evolocumab		Others
	Evolocumab is a human IgG2 monoclonal antibody that binds to human PCSK9 Proprotein Convertase Subtilisin Kexin Type 9).		Others
T13408	ZK824190		Others , Serine Protease
	ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA) as a potential treatment for multiple sclerosis(IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively).		Others , Serine Protease
T14358	Avoralstat	BCX4161	Others
	Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.		Others
T9276	SBC-115337		Others , Serine/threonin kinase
	SBC-115337 is a PCSK9 inhibitor.		Others , Serine/threonin kinase
T8645	PF-06446846		Others
	PF 06446846 is a potent and selective PCSK9 inhibitor		Others
T2626	SBC-115076	SBC115076	Others , Serine/threonin kinase
	SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.		Others , Serine/threonin kinase
T5456	WNK-IN-11	Allosteric WNK Kinase Inhibitor	Serine/threonin kinase
	WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)		Serine/threonin kinase
T6370	AEBSF hydrochloride	AEBSF HCl,Pefabloc SC	Thrombin , Serine Protease , Influenza Virus
	AEBSF hydrochloride (Pefabloc SC) is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, thrombin, plasmin, and trypsin.		Thrombin , Serine Protease , Influenza Virus
T8676	FOY 251		Others , Serine/threonin kinase , SARS-CoV
	FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.		Others , Serine/threonin kinase , SARS-CoV
T31206	Darexaban	YM 150,Darexaban, Tanexaban,YM150	Factor Xa
	Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothrombin activity at the site of blood clot (thrombus) formati...		Factor Xa
T3359	Aprotinin	Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin	Others , Serine Protease , Influenza Virus , Proteasome
	Aprotinin (Traskolan) a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activat...		Others , Serine Protease , Influenza Virus , Proteasome
T2392	Nafamostat mesylate	FUT-175	Apoptosis , Serine/threonin kinase , SARS-CoV , Serine Protease
	Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
T19763	Cetraxate hydrochloride	DV-1006,DV 1006,Cetraxate HCl,DV1006	Serine/threonin kinase
	Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.		Serine/threonin kinase
T8936	Proteinase K	proteinase K for tritirachium album,Protease K	Others
	Proteinase K (proteinase K for tritirachium album) is a nonspecific serine protease that is useful for general digestion of proteins. It is active in the presence of SDS or urea and over a wide range of pH (4-12), salt c...		Others
T2391	Camostat mesylate	FOY-S980,FOY305,Camostat mesilate	Serine/threonin kinase , SARS-CoV , Sodium Channel
	Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.		Serine/threonin kinase , SARS-CoV , Sodium Channel
T4317	PF 429242		NPC1L1 , Lipid
	PF-429242 is a competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM). It is selective for site 1 protease against a panel of serine proteases. PF-429242 inhibits rat...		NPC1L1 , Lipid
T25218	CE-2072	CE2072,CE 2072
	CE-2072 is a synthetic host serine proteases inhibitor.
T78409	Boc-Val-Pro-Arg-MCA hydrochloride	Boc-Val-Pro-Arg-MCA HCl
	Boc-Val-Pro-Arg-MCA hydrochloride (Boc-Val-Pro-Arg-MCA HCl) is a sensitive fluorescent substrate for the determination of trypsin-like serine proteases activity.
T37019	P-APMSF (hydrochloride)
	p-APMSF is an irreversible inhibitor of serine proteases with Ki values of 1.02, 1.18, 1.5, and 1.54 μM for bovine trypsin, human thrombin, bovine plasmin, and bovine Factor Xa, respectively. It is selective for these pr...
T26202	SP-Chymostatin B	alpha-Mapi
	SP-Chymostatin B is a potent inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases. It weakly inhibits human leucocyte elastase. I...
T14555	BI-1230		HCV Protease
	BI-1230 is a potent inhibitor of HCV NS3 protease, exhibiting efficacy in the low nanomolar range, and notably suppresses viral replication. This compound demonstrates high selectivity, distinguishing effectively between...		HCV Protease
T77221	Benzenecarboximidamide, hydrochloride, hydrate (1:1:x)
	Benzenecarboximidamide, hydrochloride, hydrate (1:1:x) (Benzamidine hydrochloride hydrate) is a reversible competitive trypsin-like serine proteases inhibitor with K i s of 20, 21, 97, 110, 320 and 750 μM against Tryptas...
T80094	Dansyl-Glu-Gly-Arg-Chloromethylketone
	Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor that specifically impedes serine/threonine proteases and has been shown to inhibit activated porcine factor IX [1].
T74390	VD2173
	VD2173, a macrocyclic peptide inhibitor with a side chain cyclization, effectively inhibits HGF-activating serine proteases including matriptase and hepsin, and is utilized in lung cancer research [1].
TP1013	N-CBZ-Phe-Arg-AMC	Z-FR-AMC
	N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a substrate for serine proteases, including cathepsins, kallikrein and plasmin. Absorption/emission of substrate = 330/390 nm (weak fluorescence); absorption/emission of end product (AMC) ...
T81711	N-Acetyl-DL-phenylalanine β-naphthyl ester
	N-Acetyl-DL-phenylalanine β-naphthyl ester serves as a chromogenic substrate specifically for chymotrypsin and microbial serine proteases like subtilisin [1]. This aromatic amino acid ester exhibits color changes upon en...
T36943	Aminopeptidase N Inhibitor
	Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM). It is selective for AP-N/CD13 over matrix metalloproteinase-9 (MMP-9), angiotensin converting enzyme (ACE), neutral endopeptidase (...
T39029	APC-6860
	APC-6860 is a trypsin-like serine proteases inhibitor with k i values of 0.21, 0.44, 1.5, 16.8, 20, 30 μM for uPA, trypsin, tryptase, tPA, thrombin and factor Xa, respectively. APC-6860 has a selectivity ratio for tPA ve...
T39035	FXIa-IN-6
	FXIa-IN-6 is a potent FXIa inhibitor with selectivity against most of the relevant serine proteases ( K i = 0.3 nM). FXIa-IN-6 also demonstrated excellent pharmacokinetics (PK) profile (high oral bioavailability and low ...
T62494	Cathepsin C-IN-5
	Cathepsin C-IN-5 (compound SF38) is a potent, selective, and orally active inhibitor of Cathepsin C, demonstrating IC50 values of 59.9 nM for Cat C, and showing significantly lower potency against Cat L (4.26 µM), Cat S,...
T37861	Talabostat
	Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM. Talabostat is a nonselective DPP-IV inhibitor, inhibiting DPP8/9, FAP, DPP2 ...

Compounds

Bradykinin

TP1277

Synonym:

Target: Endogenous Metabolite, Bradykinin Receptor

IPR-803

T11666

Synonym:

Target: Serine/threonin kinase

Target: Serine/threonin kinase

R-IMPP

T4058

Synonym:

Target: Others, Serine/threonin kinase

BioE-1115

T10547

Synonym:

Target: Serine/threonin kinase, Casein Kinase

Target: PAI-1, Serine/threonin kinase, Serine Protease

Benzamidine hydrochloride

T8362

Synonym: Benzamidine HCl

Target: Serine/threonin kinase, Serine Protease

SBC-110736

T4524

Synonym: SBC110736

Target: Others, Serine/threonin kinase

Target: Others, Serine Protease

Target: Others, Serine/threonin kinase

Target: Others, Serine/threonin kinase

WNK-IN-11

T5456

Synonym: Allosteric WNK Kinase Inhibitor

Target: Serine/threonin kinase

AEBSF hydrochloride

T6370

Synonym: AEBSF HCl,Pefabloc SC

Target: Thrombin, Serine Protease, Influenza Virus

FOY 251

T8676

Synonym:

Target: Others, Serine/threonin kinase, SARS-CoV

Darexaban

T31206

Synonym: YM 150,Darexaban, Tanexaban,YM150

Target: Factor Xa

Aprotinin

T3359

Synonym: Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin

Target: Others, Serine Protease, Influenza Virus, Proteasome

Nafamostat mesylate

T2392

Synonym: FUT-175

Target: Apoptosis, Serine/threonin kinase, SARS-CoV, Serine Protease

Cetraxate hydrochloride

T19763

Synonym: DV-1006,DV 1006,Cetraxate HCl,DV1006

Target: Serine/threonin kinase

Proteinase K

T8936

Synonym: proteinase K for tritirachium album,Protease K

Target: Others

Camostat mesylate

T2391

Synonym: FOY-S980,FOY305,Camostat mesilate

Target: Serine/threonin kinase, SARS-CoV, Sodium Channel

PF 429242

T4317

Synonym:

Target: NPC1L1, Lipid

CE-2072

T25218

Synonym: CE2072,CE 2072

Target:

Boc-Val-Pro-Arg-MCA hydrochloride

T78409

Synonym: Boc-Val-Pro-Arg-MCA HCl

Target:

p-APMSF (hydrochloride)

Benzenecarboximidamide, hydrochloride, hydrate (1:1:x)

T77221

Synonym:

Target:

Dansyl-Glu-Gly-Arg-Chloromethylketone

N-Acetyl-DL-phenylalanine β-naphthyl ester

T81711

Synonym:

Target:

Aminopeptidase N Inhibitor

カタログ番号	製品名	ターゲット
TN2082	Pinostrobin	Beta Amyloid , IL Receptor , Serine/threonin kinase , TNF
	Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα²(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppress...	Beta Amyloid , IL Receptor , Serine/threonin kinase , TNF
T5S0689	Demethylwedelolactone	Serine Protease
	Demethylwedelolactone is a natural product isolated from Eclipta alba, has trypsin inhibitory effect an IC50 of 3.0 μM. it exerts anti-invasive growth effect on breast cancer cells.	Serine Protease

天然物製品

Pinostrobin

TN2082

Synonym:

Target: Beta Amyloid, IL Receptor, Serine/threonin kinase, TNF

Demethylwedelolactone

T5S0689

Synonym:

Target: Serine Protease

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-01405	Kallikrein 5/KLK5 Protein, Human, Recombinant (His)	Human	Human Cells
	Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other di...
TMPY-01104	Coagulation factor XI/F11 Protein, Human, Recombinant (His)	Human	HEK293
	Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the p...
TMPY-00817	Granzyme B/GZMB Protein, Human, Recombinant (His)	Human	HEK293
	Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ...
TMPY-02258	Kallikrein 3/KLK3 Protein, Human, Recombinant (His)	Human	HEK293
	KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that i...
TMPY-01897	PRSS3 Protein, Human, Recombinant (His)	Human	HEK293
	Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on...
TMPY-02767	TPP1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Tripeptidyl-peptidase 1 (TPP1 / CLN2) is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activit...
TMPY-00686	Complement C2 Protein, Human, Recombinant (His)	Human	HEK293
	Complement component C2 is part of the classical complement pathway which plays a major role in innate immunity against infection. C2 is a glycoprotein synthesized in liver hepatocytes and several other cell types in ext...
TMPY-02154	FAP Protein, Human, Recombinant (His)	Human	HEK293
	Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
TMPJ-01204	TPSAB1 Protein, Human, Recombinant (His)	Human	Human Cells
	Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(T...
TMPY-04962	FAP Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
TMPY-04922	FAP Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
TMPY-04815	C1 inhibitor Protein, Rat, Recombinant (His)	Rat	HEK293
	Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact s...
TMPY-00916	Antithrombin III Protein, Human, Recombinant (His)	Human	HEK293
	SerpinC1, also known as antithrombin III (AT III), is a member of the serpin superfamily of serine protease inhibitors, and has been found to be a marker for disseminated intravascular coagulation (DIC) and to be of prog...
TMPY-03290	HGF Protein, Mouse, Recombinant	Mouse	HEK293
	Hepatocyte growth factor, also known as HGF, contains 4 kringle domains, 1 PAN domain, and 1 peptidase S1 domain. It belongs to the peptidase S1 family, plasminogen subfamily. The hepatocyte growth factor is secreted by ...
TMPY-01028	Ficolin 1/FCN1 Protein, Human, Recombinant (His)	Human	HEK293
	Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. The Ficolin family of proteins are characterized by the presence of a leader ...
TMPY-02327	HGF Protein, Human, Recombinant	Human	CHO
	Hepatocyte growth factor, also known as HGF, contains 4 kringle domains, 1 PAN domain, and 1 peptidase S1 domain. It belongs to the peptidase S1 family, plasminogen subfamily. The hepatocyte growth factor is secreted by ...
TMPY-01101	Coagulation factor X/F10 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the...
TMPH-00661	Ecotin Protein, E. coli O127:H6, Recombinant (His & Myc)	E. coli	E. coli
	General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
TMPY-01855	Serpin A10 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Protein Z-dependent protease inhibitor, also known as PZ-dependent protease inhibitor, SERPINA1 and ZPI, is a secreted protein that belongs to the serpin family. It is expressed by the liver and secreted in plasma. SERPI...
TMPY-01363	Serpin A11 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi...
TMPY-01893	Serpin A12 Protein, Human, Recombinant (His)	Human	HEK293
	Serpins are the largest and most diverse family of protease inhibitors. Most serpins control proteolytic cascades, certain serpins do not inhibit enzymes, but instead perform diverse functions such as storage (ovalbumin,...
TMPY-01841	Serpin I2 Protein, Human, Recombinant (His)	Human	HEK293
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl...
TMPH-02832	Serpin A5 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus
	Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extr...
TMPH-02898	SPINK2 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	As a strong inhibitor of acrosin, it is required for normal spermiogenesis. It probably hinders premature activation of proacrosin and other proteases, thus preventing the cascade of events leading to spermiogenesis defe...
TMPK-01043	VEGFC Protein, Human, Recombinant (His & Avi)	Human	HEK293
	the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet...
TMPY-06585	C1s Protein, Human, Recombinant (His)	Human	HEK293
	Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses. The classical complement pathway is triggered by C1, a complex comp...
TMPY-01589	Serpin B10 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi...
TMPY-01632	Serpin B4 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi...
TMPK-01044	VEGFC Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet...
TMPY-00732	Cathepsin C Protein, Human, Recombinant (His)	Human	HEK293
	Cathepsins are proteases found in many types of cells conserved in all animals, which have a vital role in mammalian cellular turnover such as bone resorption. The lysosomal cysteine protease Cathepsin C (CTSC), also kno...
TMPY-02128	Serpin B1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	SerpinB1 is an endogenous inhibitor of serine proteases recognized for its anti-inflammatory and host-protective properties. Serum SerpinB1 levels are elevated in patients with type 2 diabetes compared with that in healt...
TMPH-03119	SERPINB1 Protein, Pig, Recombinant (His & Myc)	Sus scrofa (Pig)	E. coli
	Neutrophil serine protease inhibitor that plays an essential role in the regulation of the innate immune response, inflammation and cellular homeostasis. Acts primarily to protect the cell from proteases released in the ...
TMPJ-00542	TPSB2 Protein, Human, Recombinant (His)	Human	Human Cells
	Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites faci...
TMPY-00323	Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST)	HCV	E. coli
	HCV NS3 displays three enzymatic activities: serine protease, NTPase, and RNA helicase. HCV NS3 serine protease, in association with NS4A, is responsible for the cleavages of NS3-NS4A, NS4A-NS4B, NS4B-NS5A, and NS5A-NS5B...
TMPJ-00557	Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His)	Human	Human Cells
	Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other di...
TMPJ-00468	KLK10 Protein, Human, Recombinant (His)	Human	Human Cells
	Kallikreins are a subgroup of Serine Proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other di...
TMPY-01105	Kallikrein 11/KLK11 Protein, Human, Recombinant (His)	Human	HEK293
	kallikrein-related peptidase 11 (KLK11), also known as hippostasin, trypsin-like serine protease, and PRSS2, is a member of the human tissue kallikrein family. It is a subgroup of serine proteases with diverse physiologi...
TMPY-00926	HAI-2/SPINT2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Choanal (CA) and gastrointestinal atresias (GA) are an important feature of syndromic congenital sodium diarrhea (sCSD), a disorder recently associated with mutations in the gene for serine protease inhibitor type 2 (SPI...
TMPY-00474	HAI-2/SPINT2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Choanal (CA) and gastrointestinal atresias (GA) are an important feature of syndromic congenital sodium diarrhea (sCSD), a disorder recently associated with mutations in the gene for serine protease inhibitor type 2 (SPI...
TMPY-02786	Kallikrein 11/KLK11 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	kallikrein-related peptidase 11 (KLK11), also known as hippostasin, trypsin-like serine protease, and PRSS2, is a member of the human tissue kallikrein family. It is a subgroup of serine proteases with diverse physiologi...
TMPJ-00149	Complement Factor D/CFD Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement a...
TMPY-04230	HAI-2/SPINT2 Protein, Human, Recombinant (His)	Human	HEK293
	Choanal (CA) and gastrointestinal atresias (GA) are an important feature of syndromic congenital sodium diarrhea (sCSD), a disorder recently associated with mutations in the gene for serine protease inhibitor type 2 (SPI...
TMPJ-01358	DPP3 Protein, Human, Recombinant (His)	Human	E. coli
	Dipeptidyl peptidase 3(DPP3), is a member of the S9B family in clan SC of the serine proteases. DPP3 has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. This c...
TMPJ-00481	CELA3A Protein, Human, Recombinant (His)	Human	Human Cells
	Chymotrypsin-Like Elastase Family Member 3A (CELA3A) is an enzyme that contains one peptidase S1 domain. ELA3A belongs to the peptidase S1 family of the Elastase subfamily. ELA3A is secreted from the pancreas as a zymoge...
TMPY-02712	Serpin B3 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was orig...
TMPJ-00832	Granzyme D/GZMD Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, b...
TMPY-00867	Kallikrein 13/KLK13 Protein, Human, Recombinant (His)	Human	HEK293
	Tissue kallikrein 13 (hK13), also known as KLK-L4 (kallikrein-like gene 4), is a member of the human tissue kallikrein family of serine proteases having diverse physiological functions in many tissues. The KLK13 gene res...
TMPY-04626	Enterokinase/EK Protein, Bovine, Recombinant	Bovine	P. pastoris
	Enterokinase is a member of the trypsin family of serine proteases. The precursor protein is cleaved into two chains which then forms a heterodimer linked by a disulfide bond. The heavy chain anchors enterokinase in the ...
TMPY-02759	Kallikrein 6/KLK6 Protein, Human, Recombinant (His)	Human	HEK293
	KLK6 (kallikrein-related peptidase 6), also known as Klk7, belongs to the peptidase S1 family, Kallikrein subfamily. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence...
TMPY-01303	Serpin A3 Protein, Human, Recombinant (His)	Human	HEK293
	SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has be...
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